Hiroyasu Kaneda,1 Takeshi Yoshida,1 Isamu Okamoto2 1Department of Medical Oncology, Kinki University, Osakasayama, Japan; 2Center for Clinical and Translational Research, Kyushu Eyeshadow Brushes University Hospital, Fukuoka, Japan Abstract: The discovery of activating mutations in the epidermal growth-factor receptor (EGFR) gene in 2004 opened a n
Background Reciprocal associations between negative parenting and child externalising problems are well documented, but measures commonly include child irritability, Plunger Cutters masking potential distinct associations for irritability and conduct problems.Aims To illuminate links between negative parenting, child conduct problems and irritabili
Choroideremia (CHM) is a rare X-linked chorioretinal dystrophy, affecting the photoreceptors, retinal pigment epithelium (RPE) and choroid, with no approved therapy.CHM is caused by mutations in the CHM gene, which encodes the ubiquitously expressed Rab escort protein Eyeshadow Brushes 1 (REP1).REP1 is involved in prenylation, a post-translational